What is the role of leukapheresis in CAR T-cell therapy?

verifiedCite
While every effort has been made to follow citation style rules, there may be some discrepancies. Please refer to the appropriate style manual or other sources if you have any questions.
Select Citation Style
Feedback
Corrections? Updates? Omissions? Let us know if you have suggestions to improve this article (requires login).
Thank you for your feedback

Our editors will review what you’ve submitted and determine whether to revise the article.

External Websites

Leukapheresis is used to collect T cells, a type of white blood cell, for chimeric antigen receptor (CAR) T-cell therapy. The T cells obtained by leukapheresis are genetically modified to kill cancer cells before being infused back into the patient. This process supports treatments for such cancers as B-cell acute lymphoblastic leukemia and B-cell non-Hodgkin lymphoma.