cefoxitin
biochemistry
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second-generation cephalosporins
- In antibiotic: Cephalosporins
second-generation cephalosporins (cefamandole, cefaclor, cefotetan, cefoxitin, and cefuroxime) have an extended antibacterial spectrum that includes greater activity against additional species of gram-negative rods. Thus, these drugs are active against Escherichia coli and Klebsiella and Proteus species (though several strains of these organisms have developed resistance). Cefamandole is active against many…
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use as antibiotic
- In gonorrhea: Diagnosis and treatment
cefoxitin became increasingly used as alternatives for eliminating N. gonorrhoeae. Some strains of the bacteria, however, later developed resistance to fluoroquinolones, and eventually multidrug-resistant strains appeared. In the early 2000s, evidence of cephalosporin-resistant N. gonorrhoeae emerged.
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