gamma-aminobutyric acid

…serotonin (5-HT) and the inhibitory gamma-aminobutyric acid (GABA) systems. Early findings of elevated serotonin in the peripheral blood (hyperserotonemia) in many autistic individuals have led scientists to investigate whether similar abnormalities are found in the brain. However, the mechanisms by which the serotonin neurotransmitter system may contribute to signs and…

…inhibitory effect of the neurotransmitter gamma-aminobutyric acid (GABA). Surgery may be performed if seizures are uncontrolled by medication.

…the inhibitory amino acids include gamma-aminobutyric acid (GABA) and glycine.

Gamma-aminobutyric acid (GABA) is the primary neurotransmitter contained in spiny striatal neurons. Other neurotransmitters found in spiny striatal neurons include substance P and enkephalin.

…that utilize the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). As a result, inhibitory signals form the basis of most communication between nuclei in the basal ganglia. Exceptions include the excitatory glutamate-releasing projections of the subthalamic nucleus and the dopamine-releasing projection neurons from the substantia nigra pars compacta.

…of the nervous system is GABA (gamma-aminobutyric acid), which acts to dampen neuronal activity.

…of the neurotransmitter GABA (gamma-aminobutyric acid). The neurons in turn project to the cells of the pars reticulata, which, by projecting fibres to the thalamus, are part of the output system of the corpus striatum.

…cells release a neurotransmitter called GABA (gamma-aminobutyric acid), which exerts inhibitory actions on certain neurons and thereby reduces the transmission of nerve impulses. These inhibitory functions enable Purkinje cells to regulate and coordinate motor movements.

…a special site on the gamma-aminobutyric acid A (GABA_A) receptor in the central nervous system. This binding action increases the receptor’s affinity to the inhibitory neurotransmitter GABA. Enhanced GABA activity reduces the transmission of neural impulses in the brain that are associated with anxiety and panic.

Neurons in the brain exhibit highly specific, high-affinity binding sites that can selectively recognize, or bind, the benzodiazepine compounds. The cellular and subcellular locations of these sites are near ion channels in the membrane that can admit chloride ions into the cell and also…

…the action of the neurotransmitter gamma-aminobutyric acid (GABA), which inhibits anxiety by reducing certain nerve-impulse transmissions within the brain. Benzodiazepines resemble barbiturates in their side effects: sleepiness, drowsiness, reduced alertness, and unsteadiness of gait. Though less dangerous than barbiturates, they can produce physical dependency even in moderate dosages, and the…

…receptors for a neurotransmitter called gamma-aminobutyric acid (GABA), which inhibits anxiety. It is possible that the interaction of benzodiazepines with these receptors facilitates the inhibitory (anxiety-suppressing) action of GABA within the brain.

gamma-aminobutyric acid (GABA), which functions to reduce the transmission of neural impulses in the brain. The drug acts specifically on GABA_A receptors, where it binds to an area that is distinct from the GABA binding site and thereby heightens inhibitory effects on neural transmission. In…