gene regulation

Experiments have shown that many of the genes within the cells of organisms are inactive much or even all of the time. Thus, at any time, in both eukaryotes and prokaryotes, it seems that a gene can be switched on or off. The…

Not all genes in a cell are active in protein production at any given time. Gene action can be switched on or off in response to the cell’s stage of development and external environment. In multicellular organisms, different kinds of cells…

…on mammalian developmental genetics, particularly gene regulation during different developmental stages and the role of genomic imprinting, in which a gene is differentially expressed depending on whether it is inherited from the mother or the father. As a professor, Tilghman devoted extensive time to the mentorship of students in science.…