lin-14
molecular genetics
Learn about this topic in these articles:
Ambros
- In Victor Ambros: Lin-4 and miRNA
…with a gene known as lin-14. Although it was apparent to Ambros and others that lin-4 somehow regulates lin-14 activity, the mechanism was a mystery.
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Ruvkun
- In Gary Ruvkun: Lin-14 and let-7
In 1985 Ruvkun joined the faculty at Massachusetts General Hospital and Harvard Medical School and continued to research developmental genetics in C. elegans. He successfully cloned the lin-14 gene, and in the early 1990s, following Ambros’s observation that lin-4 produces a very…
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