lin-14

molecular genetics

Learn about this topic in these articles:

Ambros

  • Cowinner of the 2024 Nobel Prize for Physiology or Medicine Victor Ambros
    In Victor Ambros: Lin-4 and miRNA

    …with a gene known as lin-14. Although it was apparent to Ambros and others that lin-4 somehow regulates lin-14 activity, the mechanism was a mystery.

    Read More

Ruvkun

  • Gary Ruvkun reacts after learning that he is a winner of the 2024 Nobel Prize for Physiology or Medicine.
    In Gary Ruvkun: Lin-14 and let-7

    In 1985 Ruvkun joined the faculty at Massachusetts General Hospital and Harvard Medical School and continued to research developmental genetics in C. elegans. He successfully cloned the lin-14 gene, and in the early 1990s, following Ambros’s observation that lin-4 produces a very…

    Read More