nucleosome

biology

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organization of nucleus

  • animal cell
    In cell: Nucleosomes: the subunits of chromatin

    …beadlike structure is called the nucleosome. The DNA enters and leaves a series of nucleosomes, linking them like beads along a string in lengths that vary between species of organism or even between different types of cell within a species. A string of nucleosomes is then coiled into a solenoid…

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role in cell differentiation

  • animal cell
    In cell: The differentiated state

    …complexed into repeating structures called nucleosomes, each of which contains eight molecules of histone. Active genes are found in parts of the DNA where the chromatin has an “open” configuration, in which regulatory proteins are able to gain access to the DNA. The degree to which the chromatin opens depends…

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role of histones

  • Histones and nucleosomes
    In histone

    …form nucleoprotein complexes known as nucleosomes. Each nucleosome is made up of an octamer of two copies of four different histone proteins, designated H2A, H2B, H3, and H4. DNA winds around groups of histones, helping to organize it into a compact structure known as chromatin. A so-called linker histone, H1,…

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