Antequera, city, Málaga provincia (province), in the comunidad autónoma (autonomous community) of Andalusia, southern Spain, northwest of Málaga, at the foot of the Sierra del Torcal. Neolithic dolmens (Menga, Viera, and El Romeral) attest to prehistoric occupation of the site. The city, known to

catalyst poison, substance that reduces the effectiveness of a catalyst in a chemical reaction. In theory, because catalysts are not consumed in chemical reactions, they can be used repeatedly over an indefinite period of time. In practice, however, poisons, which come from the reacting substances

Julius Caesar: Personality and reputation of Julius Caesar: As for the lost Anticato, a reply to Cicero’s eulogy of Caesar’s dead opponent Marcus Porcius Cato, it is a testimony to Caesar’s political insight that he made the time to write it, in spite of the overwhelming military, administrative, and legislative demands on him. He realized that Cato,…

Andrea Palladio: Visits to Rome and work in Vicenza: …1556, Palladio in 1554 published Le antichità di Roma (“The Antiquities of Rome”), which for 200 years remained the standard guidebook to Rome. In 1556 he collaborated with the classical scholar Daniele Barbaro in reconstructing Roman buildings for the plates of Vitruvius’ influential architectural treatise (written after 26 bce) De…

antiemetic: Anticholinergic drugs and antihistamines are effective against motion sickness. Although many are available for use, none is entirely free from side effects (e.g., dry mouth and blurred vision with the anticholinergics, drowsiness with the antihistamines). The most-effective drugs in this group are the anticholinergic drug…

anticholinesterase, any of several drugs that prevent destruction of the neurotransmitter acetylcholine by the enzyme acetylcholinesterase within the nervous system. Acetylcholine acts to transmit nerve impulses within the parasympathetic nervous system—i.e., that part of the autonomic nervous

Lars von Trier: Later films included Antichrist (2009), which agitated audiences with its graphic depiction of sexual violence within a grieving couple’s relationship, and the haunting Melancholia (2011), in which a chaotic wedding and attendant familial discord are set against a planet’s impending collision with Earth. His next film, Nymphomaniac, was…

Antichrist, the polar opposite and ultimate enemy of Christ. According to Christian tradition, he will reign terribly in the period prior to the Last Judgment. The term Antichrist first appeared in the Letters of John (1 John 2:18, 2:22, and 4:3; 2 John 1:7), and the fully developed story of

Ernest Renan: Later writings of Ernest Renan: …found expression in L’Antéchrist (1873; The Antichrist, 1896; vol. 4 of the Histoire des origines), with its satirical portrait of Nero and its apocalyptic atmosphere—replete with expectations of a cataclysmic consummation of history—assuredly the most impressive of his historical narratives. The “festival of the universe” provides a visionary end to…

Carly Simon: …Should Be” (1971) and “Anticipation” (1971). The album titled Anticipation earned her a Grammy in 1971 for best new artist. “You’re So Vain,” like the album No Secrets, reached number one on the Billboard chart in 1973. She eventually revealed the subject of the song to be actor Warren…

acclimatization: …characteristic of acclimatization is its anticipatory nature—it can develop before the change occurs. It would seem that anticipation of the need for change would be required in order to make the slow physiological preparations for climatic changes that often set in very suddenly. Anticipation of acclimatization seems to require a…

H.G. Wells: Early writings: …into higher forms, and with Anticipations (1901), Mankind in the Making (1903), and A Modern Utopia (1905), he took his place in the British public’s mind as a leading preacher of the doctrine of social progress. About this time, too, he became an active socialist, and in 1903 joined the…

anhedonia: Those affected by anticipatory anhedonia do not experience pleasure when looking forward to an activity or in expectation of gratification; in such cases, individuals often suffer from a diminished desire to participate in activities. Consummatory anhedonia is characterized by a lack of pleasure when participating in an activity…

Autolycus: …maternal grandfather, through his daughter Anticleia, of the hero Odysseus. In Homer’s Odyssey the god Hermes rewards Autolycus’s faithful sacrifices to him by granting Autolycus skill in trickery, but later ancient authors made him the god’s son. He was believed to live at the foot of Mount Parnassus and was…

anticlericalism, in Roman Catholicism, opposition to the clergy for its real or alleged influence in political and social affairs, for its doctrinairism, for its privileges or property, or for any other reason. Although the term has been used in Europe since the 12th and 13th centuries, it is

Within the history of Roman Catholicism, the term anticlericalism refers to opposition movements against Roman Catholic clergy throughout various regions and periods in history. These sentiments have arisen due to both perceived and proven corruption, doctrinairism, or other undue influence on

anticlimax, a figure of speech that consists of the usually sudden transition in discourse from a significant idea to a trivial or ludicrous one. Alexander Pope’s The Rape of the Lock uses anticlimax liberally; an example

primate: Vertebral column and posture: …of components, including an “anticlinal” vertebra situated in the mid-thoracic (upper-back) region of the spinal column and marking the transition between the forelimb and hind limb segments. In a galloping greyhound, the anticlinal vertebra is at the apex of the acute curve of the back. An anticlinal vertebra is…

petroleum: Structural traps: …most common structural traps are anticlines, upfolds of strata that appear as inverted V-shaped regions on the horizontal planes of geologic maps. About 80 percent of the world’s petroleum has been found in anticlinal traps. Most anticlines were produced by lateral pressure, but some have resulted from the draping and…

fold: An anticlinorium is a large anticline on which minor folds are superimposed, and a synclinorium is a large syncline on which minor folds are superimposed. A symmetrical fold is one in which the axial plane is vertical. An asymmetrical fold is one in which the axial…

anticoagulant, any drug that, when added to blood, prevents it from clotting. Anticoagulants achieve their effect by suppressing the synthesis or function of various clotting factors that are normally present in the blood. Such drugs are often used to prevent the formation of blood clots (thrombi)

heredity: Translation: …three unpaired nucleotides, called an anticodon. The anticodon of any one tRNA fits perfectly into the mRNA codon that codes for the amino acid attached to that tRNA; for example, the mRNA codon UUU, which codes for the amino acid phenylalanine, will be bound by the anticodon AAA. Thus, any…

coincidence counting: In anticoincidence counting, two counters are connected so that a pulse is recorded by one of them only if there is no simultaneous pulse in the other. This is useful in rejecting particles that do not originate from the source being studied.

Jawaharlal Nehru: Achievements as prime minister: …the early years after independence, anticolonialism had been the cornerstone of his foreign policy. His interest in the issue waned, however, after Zhou Enlai, the Chinese prime minister, stole the spotlight from him at the Bandung Conference of African and Asian countries that was held in Indonesia in 1955. By…

Ticlio, mountain pass of the Cordillera Central of the Peruvian Andes, about 60 miles (100 km) northeast of Lima. Through its highest part—La Cima, at an elevation of 15,807 feet (4,818 metres)—passes a branch line of the highest standard-gauge railway in the world. The railroad was built to

anticonsumerism movement, a social ideology that decries the excessive purchasing and consumption of material possessions. Anticonsumerism (and consumerism itself) focuses largely on the reasons goods are acquired—that is, on why and how certain commodities are bought and consumed by individuals.

Brocken spectre, the apparently enormously magnified shadow that an observer casts, when the Sun is low, upon the upper surfaces of clouds that are below the mountain upon which the observer stands. The apparent magnification of size of the shadow is an optical illusion that occurs when the shadow

Anticosti Island, island in the Gulf of St. Lawrence at the mouth of the St. Lawrence River, part of the Côte-Nord region, southeastern Quebec province, Canada. The island is 140 miles (225 km) long, and its greatest width is 35 miles (56 km). It rises to 625 feet (191 metres) in hills along its

Gulf of Saint Lawrence: …three northern elongated platforms: the Anticosti Platform, near the island of the same name; another platform that skirts the low northern coast of the gulf; and finally, one lying between the Eskimo Channel and Newfoundland. The reefs on these surfaces, coupled with the hazards of fog and ice, have caused…

Anticosti Island, island in the Gulf of St. Lawrence at the mouth of the St. Lawrence River, part of the Côte-Nord region, southeastern Quebec province, Canada. The island is 140 miles (225 km) long, and its greatest width is 35 miles (56 km). It rises to 625 feet (191 metres) in hills along its

animal rights: Animals and the law: …animal owners, such as criminal anticruelty statutes or civil statutes that permit owners to obtain compensation for damages inflicted on their animals. Indeed, this sort of law presently defines the field of “animal law,” which is much broader than animal rights because it encompasses all law that addresses the interests…

intellectual-property law: Internet domain names: …national system, known as the Anticybersquatting Consumer Protection Act, which is administered by the federal courts. Under the law, individuals can be fined up to $100,000 for registering a domain name in “bad faith.” Defenders of the law contended that it was crucial to protect the commercial value of trademarks…

anticyclone, any large wind system that rotates about a centre of high atmospheric pressure clockwise in the Northern Hemisphere and counterclockwise in the Southern. Its flow is the reverse of that of a cyclone

antidepressant, any member of a class of drugs prescribed to relieve depression. There are several major classes of antidepressant drugs, the best known of which include the tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs), and selective serotonin reuptake inhibitors (SSRIs). Other

antidepressant, any member of a class of drugs prescribed to relieve depression. There are several major classes of antidepressant drugs, the best known of which include the tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs), and selective serotonin reuptake inhibitors (SSRIs). Other

calculus: Differentiation and integration: This is called the (indefinite) integral of the function y = x2, and it is written as ∫x2dx. The initial symbol ∫ is an elongated S, which stands for sum, and dx indicates an infinitely small increment of the variable, or axis, over which the function is being summed.…

antidiabetic drug, any drug that works to lower abnormally high glucose (sugar) levels in the blood, which are characteristic of the endocrine system disorder known as diabetes mellitus. Diabetes is caused by the body’s inability to produce or respond to the pancreatic hormone insulin. One of the

antidiarrheal drug, any drug that relieves symptoms of diarrhea, the frequent passage of a watery loose stool. In general, the antidiarrheal drugs may be divided into different groups based on chemical or functional similarities; these groups include adsorbents, antimotility agents, and bacterial

vasopressin, hormone that plays a key role in maintaining osmolality (the concentration of dissolved particles, such as salts and glucose, in the serum) and therefore in maintaining the volume of water in the extracellular fluid (the fluid space that surrounds cells). This is necessary to protect

springbok, (Antidorcas marsupialis), graceful, strikingly marked antelope of the gazelle tribe, Antilopini (family Bovidae, order Artiodactyla). The springbok is native to the open, treeless plains of southern Africa. It once roamed in enormous herds but is now much reduced in numbers. It is the

Ulisse Aldrovandi: …official pharmacopoeia that Aldrovandi wrote, Antidotarii Bononiensis Epitome (1574), describing the constituents and properties of drugs, became a model for such works.

Chick Corea: He won another Grammy for Antidote (2019), which he recorded with his Spanish Heart Band. He also received multiple Latin Grammy Awards.

Jacques Rabemananjara: …reprieve, and the poems of Antidote, written while he was imprisoned in 1947–50 and published in 1961, reflect his anger at the injustice imposed on him and his political hopes for the future.

antidote, Remedy to counteract the effects of a poison or toxin. Administered by mouth, intravenously, or sometimes on the skin, it may work by directly neutralizing the poison; causing an opposite effect in the body; binding to the poison to prevent its absorption, inactivate it, or keep it from

Lorenzo Valla: …and Valla replied in his Antidoti in Poggium (“Antidotes to Poggio”). Both scholars are seen at their worst here, hurling at one another accusations of ignorance, of barbarism, of plagiarism, and even worse. Benedetto Morandi, a notary from Bologna, assailed Valla for his disrespect in arguing that Livy had made…

countervailing duty: …duties are commonly known as antidumping duties. Countervailing duties are allowed under Article VI of the General Agreement on Tariffs and Trade, a trade agreement administered by the World Trade Organization.

positron, positively charged subatomic particle having the same mass and magnitude of charge as the electron and constituting the antiparticle of a negative electron. The first of the antiparticles to be detected, positrons were discovered by Carl David Anderson in cloud-chamber studies of the

antiemetic, any drug that is used to prevent vomiting. Broadly, antiemetics may be divided into two groups: drugs that are effective in combating motion sickness and drugs that are effective against nausea and vomiting due to other causes. The exact way in which these drugs work is not known,

musical performance: The 19th century: …in a sense by the Concerts of Antient Music (1776–1848) in London. The stated policy of this musical group was not to perform music less than 20 years old (but they often updated the compositions with added brass parts). The revival of interest in the music of Giovanni Pierluigi da…

antiepileptic drug, any drug that is effective in the treatment of epilepsy, a chronic disorder of the central nervous system that is characterized by sudden and recurrent seizures. The treatment of epilepsy generally is directed toward reducing the frequency of seizures. An accurate diagnosis of

antiestrogen, any substance that blocks the synthesis or action of the hormone estrogen. Estrogen can be both a beneficial and a harmful hormone. It maintains skeletal strength by preventing the loss of bone and enhancing calcium retention. However, estrogen causes the proliferation of cells in the

Battle of Antietam, (September 17, 1862), in the American Civil War (1861–65), a decisive engagement that halted the Confederate invasion of Maryland, an advance that was regarded as one of the greatest Confederate threats to Washington, D.C. The Union name for the battle is derived from Antietam

antifa, a broad and decentralized political movement comprising individuals and groups who believe that fascism continues to pose a unique threat to democratic and peaceful societies and must be combatted through extraordinary, radical, and, in some cases, violent and illegal means. The term antifa

antifa, a broad and decentralized political movement comprising individuals and groups who believe that fascism continues to pose a unique threat to democratic and peaceful societies and must be combatted through extraordinary, radical, and, in some cases, violent and illegal means. The term antifa

Anti-Fascist Council for the National Liberation of Yugoslavia, umbrella organization established during World War II by the Communist Party of Yugoslavia to coordinate the military campaigns of Josip Broz Tito’s Partisans and the administrative activities of local “liberation committees.” AVNOJ

chemoreception: Phagostimulation: Although most secondary compounds are deterrent to the vast majority of species, there are some cases in which these compounds act as essential sign stimuli for an animal, indicating that it has the correct food. This is true for many insects that are oligophagous or monophagous on plants that contain…

weak interaction: …angular momentum, or spin—and right-handed antifermions. Particles interact through the weak interaction by exchanging force-carrier particles known as the W and Z particles. These particles are heavy, with masses about 100 times the mass of a proton, and it is their heaviness that defines the extremely short-range nature of the…

antiferromagnetism, type of magnetism in solids such as manganese oxide (MnO) in which adjacent ions that behave as tiny magnets (in this case manganese ions, Mn2+) spontaneously align themselves at relatively low temperatures into opposite, or antiparallel, arrangements throughout the material so

sulfide mineral: …eight metal cations—is called the antifluorite structure. It is the arrangement of some of the more valuable precious metal tellurides and selenides among which is hessite (Ag2Te), the ore mineral of silver.

antifreeze, any substance that lowers the freezing point of water, protecting a system from the ill effects of ice formation. Antifreezes, such as ethylene glycol or propylene glycol, commonly added to water in automobile cooling systems prevent damage to radiators. Additives to prevent freezing of

bearing: …rollers; these are known as rolling bearings. In the illustration, the inner race turns with the shaft.

antifungal drug, any substance that acts selectively against a fungal pathogen (disease-causing organism) in the treatment of fungal infection (mycosis). The major groups of antifungals are the polyenes, the azoles, and the allyamines; these groups are distinguished primarily by chemical structure

antigen, substance that is capable of stimulating an immune response, specifically activating lymphocytes, which are the body’s infection-fighting white blood cells. In general, two main divisions of antigens are recognized: foreign antigens (or heteroantigens) and autoantigens (or self-antigens).

antibody: Antibodies and B cells: …distinguish antigens through proteins, called antigen receptors, found on their surfaces. An antigen receptor is basically an antibody protein that is not secreted but is anchored to the B-cell membrane.

allergy: …effects are the result of antibody-antigen responses (i.e., they are the products of B-cell stimulation). These can be divided into three basic types.

immune system: Basic structure of the immunoglobulin molecule: …is an area called the antigen-binding, or antibody-combining, site, which is formed by a portion of the heavy and light chains. Every immunoglobulin molecule has at least two of these sites, which are identical to one another. The antigen-binding site is what allows the antibody to recognize a specific part…

prostate cancer: Treatment: …based on the collection of antigen-presenting cells (APCs; a type of immune cell) from the patient’s blood using a procedure known as leukapheresis (the separation of leukocytes, or white blood cells, from other blood components). The APCs are then cultured in a laboratory, where they are grown in the presence…

epitope, portion of a foreign protein, or antigen, that is capable of stimulating an immune response. An epitope is the part of the antigen that binds to a specific antigen receptor on the surface of a B cell. Binding between the receptor and epitope occurs only if their structures are

antigenic drift, random genetic mutation of an infectious agent resulting in minor changes in proteins called antigens, which stimulate the production of antibodies by the immune systems of humans and animals. These mutations typically produce antigens to which only part of a population may be

antigenic shift, genetic alteration occurring in an infectious agent that causes a dramatic change in a protein called an antigen, which stimulates the production of antibodies by the immune systems of humans and other animals. Antigenic shift has been studied most extensively in influenza type A

protozoan: Protozoans and disease: …alternate forms are known as antigenic variants, and it has been estimated that each species may have as many as 100 to 1,000 such variants. The host must produce a new set of antibodies against each new variant, and in the meantime the parasite has time to replenish its numbers.…

antiglobalization, social movement that emerged at the turn of the 21st century against neoliberal globalization, a model of globalization based on the promotion of unfettered markets and free trade. Looking at definitions of globalization by important social scientists such as Anthony Giddens,

blood group: Coombs test: Coombs serum (also called antihuman globulin) is made by immunizing rabbits with human gamma globulin. The rabbits respond by making antihuman globulin (i.e., antibodies against human gamma globulin and complement) that is then purified before use. The antihuman globulin usually contains antibodies against IgG and…

blood group: Coombs test: When an incomplete antibody reacts with the red cells in saline solution, the antigenic sites become coated with antibody globulin (gamma globulin), and no visible agglutination reaction takes place. The presence of gamma globulin on cells can be detected by the Coombs test,…

Antigone, in Greek legend, the daughter born of the unwittingly incestuous union of Oedipus and his mother, Jocasta. After her father blinded himself upon discovering that Jocasta was his mother and that, also unwittingly, he had slain his father, Antigone and her sister Ismene served as Oedipus’

Sophocles: Antigone: Antigone is the daughter of Oedipus, the former king of Thebes. She is willing to face the capital punishment that has been decreed by her uncle Creon, the new king, as the penalty for anyone burying her brother Polyneices. (Polyneices has just been killed…

Walter Hasenclever: …by a firing squad, and Antigone (1917), a pacifist-slanted interpretation of Sophocles’ play. In his best-known work, Die Menschen (1918; “Humanity”), Expressionist techniques are carried to an extreme form. The characters are symbolic types, speech is reduced to staccato monosyllables, and meaning is conveyed by pantomime and stylized overacting. Later,…

boarfish: The two genera, Antigonia and Capros, are placed in different subfamilies. A typical species, A. capros, reaches a length of about 18 cm (7 inches).

boarfish: capros, reaches a length of about 18 cm (7 inches).

Antigonid dynasty, ruling house of ancient Macedonia from 306 to 168 bce. The Antigonid dynasty was established when Demetrius I Poliorcetes, the son of Antigonus I Monophthalmus, ousted Cassander’s governor of Athens, Demetrius of Phaleron, and conquered the island of Cyprus, thereby giving his

Antigonus I Monophthalmus was a Macedonian general under Alexander the Great who founded the Macedonian dynasty of the Antigonids (306–168 bce), becoming king in 306. An exceptional strategist and combat leader, he was also an astute ruler who cultivated the friendship of Athens and other Greek

Antigonus I Monophthalmus was a Macedonian general under Alexander the Great who founded the Macedonian dynasty of the Antigonids (306–168 bce), becoming king in 306. An exceptional strategist and combat leader, he was also an astute ruler who cultivated the friendship of Athens and other Greek

Antigonus II Gonatas was the king of Macedonia from 276 bc who rebuilt his kingdom’s power and established its hegemony over Greece. Antigonus II was the son of Demetrius I Poliorcetes and grandson of Antigonus I. While Demetrius was busy fighting in Macedonia and Asia Minor, Antigonus, as his

Antigonus III Doson was the king of Macedonia (from 227 bc) who, in defeating Cleomenes of Sparta, ended that city’s long independence. His surname may have signified “one who is about to give but never does.” Antigonus, a descendant of Antigonus I, was the son of Demetrius II (a half brother of

coin: Coinage in Judaea: Antigonus Mattathias (40–37 bc), the last of the Maccabees, introduced the seven-branched candlestick as a type. Under the Herodian dynasty, from 37 bc, Greek alone was found on Judaean coins. Herod Philip (4 bc–ad 34) gravely infringed Jewish convention by showing the effigy of the…

antigorite, mineral, a polymorph of serpentine

quark: Quark colours: …quarks, and their opposites, antired, antigreen, and antiblue, are ascribed to antiquarks. According to QCD, all combinations of quarks must contain mixtures of these imaginary colours that cancel out one another, with the resulting particle having no net colour. A baryon, for example, always consists of a combination of one…

Antigua and Barbuda, islands that form an independent state in the Lesser Antilles in the eastern Caribbean Sea, at the southern end of the Leeward Islands chain. There is one dependency, the small island of Redonda. The capital is St. John’s, on Antigua. Antigua’s coastline is intricate, with bays

rectangular national flag with red triangles at the hoist and fly ends and a central triangular area of white, blue, and black, incorporating a golden sun. Its width-to-length ratio is approximately 2 to 3.The coat of arms granted in 1909 to the Leeward Islands (including Antigua and its former

history of Antigua and Barbuda, a survey of the notable events and people in the history of Antigua and Barbuda from the 15th century to the present. Located in the Lesser Antilles in the eastern Caribbean Sea, Antigua and Barbuda consists of three islands: Antigua, Barbuda, and Redonda, a small

Antigua Guatemala, city, southwestern Guatemala, at an elevation of 5,029 feet (1,533 metres). Capital of the former captaincy general, Antigua Guatemala was once the most important seat of Spanish colonial government between Mexico City and Lima, Peru. Founded as Santiago de los Caballeros de

antimatter: …heaviest antiatom, the nucleus of antihelium-4, which consists of two antiprotons and two antineutrons. Since antihelium-4 is produced so rarely in nuclear collisions, its detection in space by an instrument such as the Alpha Magnetic Spectrometer on the International Space Station would imply the existence of large amounts of antimatter…

human ear: Outer ear: An inner, concentric ridge, the antihelix, surrounds the concha and is separated from the helix by a furrow, the scapha, also called the fossa of the helix. In some ears a little prominence known as Darwin’s tubercle is seen along the upper, posterior portion of the helix; it is the…

anthelmintic, any drug that acts against infections caused by parasitic worms (helminths). Helminths can be divided into three groups: cestodes, or tapeworms; nematodes, or roundworms; and trematodes, or flukes. The helminths differ from other infectious organisms in that they have a complex body

hemophilia: …A, the missing substance is factor VIII. The increased tendency to bleeding usually becomes noticeable early in life and may lead to severe anemia or even death. Large bruises of the skin and soft tissue are often seen, usually following injury so trivial as to be unnoticed. There may also…

antihero, a protagonist of a drama or narrative who is notably lacking in heroic qualities. This type of character has appeared in literature since the time of the Greek dramatists and can be found in the literary works of all nations. Examples include the title characters of Miguel de Cervantes’s

antihistamine, any of a group of synthetic drugs that selectively counteract the pharmacological effects of histamine, following its release from certain large cells (mast cells) within the body. Antihistamines replace histamine at one or the other of the two receptor sites at which it becomes

antimatter: …an ordinary atom—in this case, antihydrogen, the simplest antiatom, consisting of a positron in orbit around an antiproton nucleus. They did so by firing antiprotons through a xenon-gas jet. In the strong electric fields surrounding the xenon nuclei, some antiprotons created pairs of electrons and positrons; a few of the…

cardiovascular drug: Drugs affecting the blood vessels: Most antihypertensive drugs have a variety of unwanted effects, such as drowsiness, dizziness on standing (due to an excessive postural fall in arterial pressure), impotence, and allergic reactions. Though often fairly minor, side effects are a serious problem because of the long-term nature of antihypertensive therapy,…